Carpal Tunnel: Boundaries, Contents and the Median Nerve

By Dr Richard Miller, MBChB FRCS · Reviewed

The carpal tunnel is a fibro-osseous passage on the palmar side of the wrist, formed by the arch of the carpal bones and roofed by the flexor retinaculum. It transmits the median nerve and nine long flexor tendons into the hand, and compression of the nerve here causes carpal tunnel syndrome.

Carpal Tunnel · key facts

Boundaries
Carpal bones medially, laterally and posteriorly; flexor retinaculum anteriorly
Roof
Flexor retinaculum (transverse carpal ligament)
Floor
Palmar surfaces of the carpal bones and their ligaments
Contents
Median nerve; 4 FDS, 4 FDP and FPL tendons
Retinaculum attachments
Pisiform and hook of hamate medially; scaphoid and trapezium tubercles laterally
Outside the tunnel
Ulnar nerve and artery, palmaris longus, palmar cutaneous branch of median nerve
Clinical relevance
Carpal tunnel syndrome; decompression by dividing the retinaculum
3D model of the carpal tunnel: flexor digitorum superficialis, flexor carpi radialis, flexor digitorum profundus and 4 more
3D model showing the flexor digitorum superficialis, flexor carpi radialis, flexor digitorum profundus and 4 more.BodyParts3D, © The Database Center for Life Science licensed under CC Attribution 4.0 International

Boundaries and contents

The carpal tunnel is bounded by bone on three sides and by the flexor retinaculum in front. The carpal bones form a transverse arch that is concave anteriorly. The retinaculum bridges that arch like a bowstring and turns the groove into a closed tunnel.

The flexor retinaculum

The flexor retinaculum is a thick band of deep fascia, also called the transverse carpal ligament. It attaches medially to the pisiform and the hook of the hamate, and laterally to the tubercle of the scaphoid and the tubercle of the trapezium. Its proximal edge lies at the level of the distal wrist crease. It holds the long flexor tendons against the carpus so they do not bowstring when the wrist flexes. It also anchors the thenar and hypothenar muscles, which arise partly from its anterior surface.

What passes through

Ten structures pass through the tunnel:

  • Median nerve, the most superficial structure, lying just deep to the retinaculum on the lateral side.
  • Four tendons of flexor digitorum superficialis (FDS), with the tendons to the middle and ring fingers lying anterior to those for the index and little fingers.
  • Four tendons of flexor digitorum profundus (FDP), lying deepest, side by side on the floor.
  • Tendon of flexor pollicis longus (FPL), on the lateral side.

The FDS and FDP tendons share the common flexor sheath (ulnar bursa). The FPL tendon has its own synovial sheath (radial bursa). The tendon of flexor carpi radialis does not run in the main tunnel: it passes through a separate compartment formed by a split in the lateral attachment of the retinaculum, grooving the trapezium.

Relations: structures outside the tunnel

Several structures cross the front of the wrist superficial to the flexor retinaculum, and the examiner expects them named. They are not affected when the median nerve is compressed in the tunnel.

  • Ulnar nerve and ulnar artery pass through Guyon's canal (the ulnar canal), between the pisiform and the hook of the hamate, superficial to the retinaculum.
  • Palmaris longus tendon, where present, runs over the retinaculum and blends with the palmar aponeurosis.
  • Palmar cutaneous branch of the median nerve arises in the distal forearm and passes superficial to the retinaculum to supply the skin of the central palm and thenar eminence.
  • Palmar cutaneous branch of the ulnar nerve supplies the skin over the hypothenar eminence.
  • Flexor carpi ulnaris inserts into the pisiform, medial to the tunnel.

The median nerve in the tunnel

The median nerve enters the hand through the tunnel and divides at its distal edge into a recurrent motor branch and digital branches. The recurrent (thenar) branch curls back around the distal border of the retinaculum to supply abductor pollicis brevis, opponens pollicis and the superficial head of flexor pollicis brevis. Its origin varies: it may arise within the tunnel and pierce the retinaculum, which puts it at risk during surgery.

The digital branches carry sensation from the palmar surface of the thumb, index, middle and lateral half of the ring finger, including the nail beds. They also supply the first and second lumbricals.

Median nerve branchRelation to retinaculumTerritory
Palmar cutaneous branchSuperficial to itSkin of central palm and thenar eminence
Recurrent motor branchUsually arises at its distal edgeAbductor pollicis brevis, opponens pollicis, flexor pollicis brevis (superficial head)
Palmar digital nervesBeyond its distal edgeLateral three and a half digits; lumbricals 1 and 2

Clinical relevance

Carpal tunnel syndrome is compression of the median nerve in this rigid space, and it is the commonest entrapment neuropathy of the upper limb. Anything that swells the contents or narrows the tunnel raises the pressure: pregnancy, hypothyroidism, rheumatoid synovitis, diabetes, acromegaly and malunited distal radius fractures.

  • Symptoms are tingling, numbness and pain in the thumb, index and middle fingers, typically worse at night.
  • The palm is spared because the palmar cutaneous branch runs superficial to the retinaculum.
  • Late signs are wasting of the lateral thenar eminence and weakness of thumb abduction, tested against resistance with the thumb pointing to the ceiling.
  • Provocation tests include Tinel's sign (tapping over the nerve) and Phalen's test (sustained wrist flexion).

Carpal tunnel decompression divides the retinaculum along its ulnar side, through an incision in line with the radial border of the ring finger. Staying ulnar protects the recurrent motor branch and the palmar cutaneous branch, which both lie radially.

How it is examined

On a cadaveric spotter, in an OSPE and in MRCS Part B anatomy.

  • The commonest spotter question is 'name the structures that pass through the carpal tunnel': median nerve plus FDS x4, FDP x4 and FPL. Flexor carpi radialis travels in its own split of the retinaculum, so do not list it as tunnel contents.
  • A pin on a flat, broad white structure just deep to the retinaculum on the lateral side is the median nerve, not a flexor tendon. Tendons are round and glistening; the nerve is flatter and has visible fascicles.
  • Expect the follow-up 'why is the palm spared in carpal tunnel syndrome?': the palmar cutaneous branch arises proximal to the wrist and passes superficial to the retinaculum.
  • Know the four bony attachments of the retinaculum (pisiform, hook of hamate, scaphoid tubercle, trapezium tubercle) and that the ulnar nerve and artery lie superficial to it in Guyon's canal.
  • On a prosection the FDS tendons are superficial to FDP. The middle and ring finger FDS tendons sit in front of the index and little finger tendons.

Key points

  • The carpal tunnel lies between the carpal arch and the flexor retinaculum.
  • It transmits ten structures: the median nerve and nine long flexor tendons.
  • Flexor carpi radialis runs in a separate compartment within the retinaculum.
  • The ulnar nerve and artery, palmaris longus and the palmar cutaneous branch of the median nerve pass superficial to it.
  • Carpal tunnel syndrome spares palmar skin sensation and later weakens thumb abduction.
  • Surgical release divides the retinaculum on its ulnar side to protect the recurrent motor branch.

Common questions

What passes through the carpal tunnel?

Ten structures pass through the carpal tunnel: the median nerve, the four tendons of flexor digitorum superficialis, the four tendons of flexor digitorum profundus and the tendon of flexor pollicis longus. The median nerve is the most superficial, lying just under the flexor retinaculum. Flexor carpi radialis runs in a separate compartment within the retinaculum, and the ulnar nerve and artery pass superficial to it.

Where does the flexor retinaculum attach?

The flexor retinaculum attaches medially to the pisiform and the hook of the hamate, and laterally to the tubercle of the scaphoid and the tubercle of the trapezium. It spans the concave palmar surface of the carpal bones, converting their groove into the carpal tunnel. Its proximal edge lies at the distal wrist crease, and the thenar and hypothenar muscles arise partly from its front.

Why is sensation in the palm normal in carpal tunnel syndrome?

Palmar sensation is normal because the skin of the central palm and thenar eminence is supplied by the palmar cutaneous branch of the median nerve. This branch leaves the main nerve in the distal forearm and crosses superficial to the flexor retinaculum, so it escapes compression inside the tunnel. Numbness confined to the digits therefore points to the carpal tunnel rather than a more proximal lesion.

Is the ulnar nerve in the carpal tunnel?

No. The ulnar nerve and ulnar artery pass through Guyon's canal, which lies superficial to the flexor retinaculum between the pisiform and the hook of the hamate. They are therefore outside the carpal tunnel. This is why carpal tunnel syndrome does not affect the little finger or the intrinsic muscles supplied by the ulnar nerve, such as the interossei and adductor pollicis.

References

  1. Gray's Anatomy: The Anatomical Basis of Clinical Practice. Standring S (ed). Elsevier. 42nd edition, 2020.
  2. Moore's Clinically Oriented Anatomy. Moore KL, Dalley AF, Agur AMR. Wolters Kluwer. 9th edition, 2022.
  3. Last's Anatomy: Regional and Applied. Elsevier.

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